Development of Ultrafine–Grained and Nanostructured Bioinert Alloys Based on Titanium, Zirconium and Niobium and Their Microstructure, Mechanical and Biological Properties

For this paper, studies of the microstructure as well mechanical and biological properties bioinert titanium, zirconium, niobium alloys in their nanostructured (NS) ultrafine-grained (UFG) states have been completed. The NS UFG were formed by a combined two-step method severe plastic deformation (SPD), first with multidirectional forging (MDF) or pressing into symmetrical channel (PSC) at given temperature regime, then subsequent multi-pass groove rolling (MPGR) room temperature, pre-recrystallization annealing. Annealing increased plasticity without changing grain size. structure, an average size structural elements no more than 0.3 ?m, was result applying SPD This structure presented significant improvement characteristics alloys, comparison coarse-grained (CG) small-grained (SG) states. At same time, although formation leads to increase yield strength tensile elastic modulus did not change. In terms biocompatibility, cultivation MG-63 osteosarcoma cells on polished sandblasted substrates demonstrated high cell viability after 10 days good adhesion surface.